Building on 30 years of continuing education courses, the Mayo Clinic Nicotine Dependence Center is partnering with Truth Initiative to host the 2025 national conference highlighting the intersection between tobacco control policy and practice. Amidst an evolving tobacco product landscape and scientific evidence, the course will educate attendees about the latest science, treatment best practices, and policy considerations. Attendees will explore a range of challenges and opportunities to deliver tobacco dependence treatment to reduce prevalence and improve the nation's health.