The Graymoor Spiritual Life Center offers a year-round schedule of weekend, weekday, and evening retreats and programs designed for both groups and individuals, including married couples, seniors, young adults, clergy, and men and women in recovery. Others focus on specific topics that meet proven needs e.g., spirituality of the twelve steps, what Christians can learn from the insights and practices of Buddhists, etc.

The Center also hosts meetings, conferences, and days of renewal for parish and church groups, high school and college students, and denominational and interreligious organizations. It provides chapel space, meeting rooms, dining facilities, and overnight accommodations.

The Center is also the location for weekly holy hours and Centering Prayer experiences and regular AA, NA, Alanon, and Recovery, Inc., meetings.

The Graymoor Spiritual Life Center is located at 1320 Route 9 in Garrison, NY, five miles north of Peekskill, NY, and 13 miles south of I-84. Take MetroNorth's Hudson River Line from Grand Central (or 125th Street) to Peekskill, taxi from Peekskill to Graymoor.